Abstract
Epstein-Barr virus- (EBV-)transformed B cells were obtained from a patient with myasthenia gravis, who was also the donor of a T cell line specific for acetylcholine receptor (AChR). After three months of culture, the EBV-transformed B cells could effectively present native membrane-bound AChR to autologous AChR-specific T cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antigen-Presenting Cells / immunology*
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B-Lymphocytes / immunology*
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Cell Transformation, Viral
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Cells, Cultured
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Herpesvirus 4, Human
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Humans
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Lymphocyte Activation
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Myasthenia Gravis / immunology
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Receptors, Nicotinic / immunology*
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T-Lymphocytes / immunology*
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Time Factors
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Torpedo