Safety and efficacy of vismodegib in relapsed/refractory acute myeloid leukaemia: results of a phase Ib trial

Br J Haematol. 2019 May;185(3):595-598. doi: 10.1111/bjh.15571. Epub 2018 Sep 11.
No abstract available

Keywords: Hedgehog signalling; leukaemia; stem cells; vismodegib.

Publication types

  • Clinical Trial, Phase I
  • Letter
  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anilides / administration & dosage*
  • Anilides / adverse effects
  • Female
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy*
  • Male
  • Middle Aged
  • Pyridines / administration & dosage*
  • Pyridines / adverse effects

Substances

  • Anilides
  • HhAntag691
  • Pyridines