Pharmacotherapy for the pseudobulbar affect in individuals who have sustained a traumatic brain injury: a systematic review protocol

Fiona J Clay; Amelia J Hicks; Luke A Perry; Jennie L Ponsford; Mahesh Jayaram; Malcolm Hopwood

doi:10.11124/JBISRIR-2017-003648

Pharmacotherapy for the pseudobulbar affect in individuals who have sustained a traumatic brain injury: a systematic review protocol

JBI Database System Rev Implement Rep. 2018 Sep;16(9):1739-1757. doi: 10.11124/JBISRIR-2017-003648.

Authors

Fiona J Clay^{1

2

3}, Amelia J Hicks⁴, Luke A Perry¹, Jennie L Ponsford⁴, Mahesh Jayaram¹, Malcolm Hopwood^{1

5}

Affiliations

¹ Department of Psychiatry, University of Melbourne, Melbourne, Australia.
² Department of Forensic Medicine, Monash University, Melbourne, Australia.
³ Joanna Briggs Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia.
⁴ Monash-Epworth Rehabilitation Research Centre, Monash Institute of Cognitive and Clinical Neurosciences, School of Psychological Sciences, Monash University, Melbourne, Australia.
⁵ Professorial Psychiatry Unit Albert Road Clinic, Department of Psychiatry, University of Melbourne, Melbourne, Australia.

PMID: 30204664
DOI: 10.11124/JBISRIR-2017-003648

Abstract

The objective of this systematic review is to synthesize current evidence on the effectiveness of pharmacotherapy as compared to all comparators for the management of pseudobulbar affect in adults 16 years and over who have sustained a traumatic brain injury. The specific review question is: What is the effectiveness of pharmacotherapy for the management of pseudobulbar affect in adults 16 years and over who have sustained a traumatic brain injury?

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Affect
Affective Symptoms / drug therapy*
Affective Symptoms / etiology
Brain Injuries, Traumatic / complications
Brain Injuries, Traumatic / drug therapy
Brain Injuries, Traumatic / psychology*
Crying*
Humans
Laughter*
Mental Disorders / drug therapy*
Mental Disorders / etiology
Neurotransmitter Agents / therapeutic use*
Research Design
Systematic Reviews as Topic

Substances

Neurotransmitter Agents