Gender differences and lung cancer risk in occupational chefs: analyzing more than 350,000 chefs in Taiwan, 1984-2011

Int Arch Occup Environ Health. 2019 Jan;92(1):101-109. doi: 10.1007/s00420-018-1358-8. Epub 2018 Sep 18.

Abstract

Objectives: Cooking oil fumes (COFs) contain many carcinogens. We investigated the association between COFs and incidence risk of any cancer and lung cancer in chefs.

Methods: We identified Chinese food chefs and non-Chinese food chefs from Taiwan's national database of certified chefs in 1984-2007. Of them, 379,275 had not been diagnosed as having any cancer before chef certification. We followed them in Taiwan's Cancer Registry Database (1979-2010) and Taiwan's National Death Statistics Database (1985-2011) for any newly diagnosed cancer or lung cancer.

Results: 378,126 and 379,215 chefs were included for risk analysis of cancer and lung cancer, respectively. 6099 chefs developed cancer and 339 developed lung cancer over the follow-up periods of 4,183,550 and 4,220,163 person-years, respectively. Compared to non-Chinese food chefs, the adjusted IRR of cancer for Chinese food chefs was 1.69 (95% CI 1.51-1.89). For lung cancer, the risk was significantly higher among Chinese food chefs who had been certified for more than 5 years (adjusted IRR 2.12, 95% CI 1.32-3.40). This increased risk was pronounced in female chefs (adjusted IRR 4.73, 95% CI 1.74-12.86).

Conclusions: Chinese food chefs had an increased risk of cancer and lung cancer, particularly in females.

Keywords: Cooking oil fumes; Gender; Lung cancer; Occupational chefs.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Carcinogens
  • Cooking / methods*
  • Female
  • Food Handling / methods
  • Humans
  • Incidence
  • Inhalation Exposure
  • Lung Neoplasms / epidemiology*
  • Lung Neoplasms / etiology
  • Male
  • Middle Aged
  • Neoplasms / epidemiology*
  • Neoplasms / etiology
  • Occupational Exposure / adverse effects*
  • Oils*
  • Risk Factors
  • Sex Factors
  • Taiwan / epidemiology

Substances

  • Carcinogens
  • Oils