LRP4 antibody positive amyotrophic lateral sclerosis patients display neuropil-reactive IgG and enhanced serum complement levels

Immunol Lett. 2018 Nov:203:54-56. doi: 10.1016/j.imlet.2018.09.011. Epub 2018 Sep 15.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aged
  • Amyotrophic Lateral Sclerosis* / blood
  • Amyotrophic Lateral Sclerosis* / immunology
  • Amyotrophic Lateral Sclerosis* / pathology
  • Autoantibodies* / blood
  • Autoantibodies* / immunology
  • Complement System Proteins* / immunology
  • Complement System Proteins* / metabolism
  • Female
  • HEK293 Cells
  • Humans
  • Immunoglobulin G* / blood
  • Immunoglobulin G* / immunology
  • LDL-Receptor Related Proteins* / immunology
  • LDL-Receptor Related Proteins* / metabolism
  • Male
  • Middle Aged
  • Neuropil* / immunology
  • Neuropil* / metabolism
  • Neuropil* / pathology

Substances

  • Autoantibodies
  • Immunoglobulin G
  • LDL-Receptor Related Proteins
  • LRP4 protein, human
  • Complement System Proteins