Increased STAT1 Amounts Correlate with the Phospho-STAT1 Level in STAT1 Gain-of-function Defects

J Clin Immunol. 2018 Oct;38(7):745-747. doi: 10.1007/s10875-018-0557-0. Epub 2018 Oct 9.

Authors

Andrea R Bernasconi¹, Judith Yancoski², Mariana Villa², Matías M Oleastro², Miguel Galicchio³, Jorge G Rossi²

Affiliations

¹ Immunology and Rheumatology Department, Hospital de Pediatría "Dr. Juan P. Garrahan", Combate de los Pozos, 1881, Buenos Aires, Argentina. arbernasconi@yahoo.com.ar.
² Immunology and Rheumatology Department, Hospital de Pediatría "Dr. Juan P. Garrahan", Combate de los Pozos, 1881, Buenos Aires, Argentina.
³ Allergy and Immunology Department, Hospital de Niños "Víctor J. Vilela", Virasoro, 1855, Rosario, Santa Fe, Argentina.

PMID: 30302727
DOI: 10.1007/s10875-018-0557-0

No abstract available

Keywords: STAT1 level; flow cytometry; gain-of-function.

Publication types

Letter

MeSH terms

Biomarkers
Gain of Function Mutation*
Genetic Association Studies*
Genetic Predisposition to Disease*
Humans
Immunophenotyping
Leukocytes, Mononuclear / metabolism
Phenotype
Phosphorylation
STAT1 Transcription Factor / genetics*
STAT1 Transcription Factor / metabolism*

Substances

Biomarkers
STAT1 Transcription Factor
STAT1 protein, human