Reversible Parkinsonism and Rapidly Progressive Dementia Due to Dural Arteriovenous Fistula: Case Series and Literature Review

Mov Disord Clin Pract. 2017 Mar 27;4(4):607-611. doi: 10.1002/mdc3.12480. eCollection 2017 Jul-Aug.

Abstract

Background: Dural arteriovenous fistula (dAVF) rarely presents with a syndrome of reversible parkinsonism and rapidly progressive dementia, which has been described in 19 patients to date. However, its presenting features, pathophysiology, and response to treatment have not been reviewed.

Methods: We report the clinical course and treatment of two novel patients with this syndrome.

Results: Despite severe presentations, both patients recovered fully after fistula obliteration.

Conclusions: Atypical parkinsonism with early cognitive changes and other focal neurological signs, along with features such as pulsatile tinnitus or worsening headache, should raise the possibility of dAVF. When treated, this syndrome is nearly always reversible, highlighting the importance of early diagnosis.

Keywords: dementia; direct sinus puncture; dural arteriovenous fistula; parkinsonism; reversible.

Publication types

  • Case Reports