Adiposity predicts low cardiorespiratory fitness in individuals with metabolic diseases

Andy Shaw; David Houghton; Kate Hallsworth; Djordje G Jakovljevic; Michael I Trenell; Sophie Cassidy

doi:10.1016/j.diabres.2018.10.022

Adiposity predicts low cardiorespiratory fitness in individuals with metabolic diseases

Diabetes Res Clin Pract. 2018 Dec:146:300-304. doi: 10.1016/j.diabres.2018.10.022. Epub 2018 Nov 2.

Authors

Andy Shaw¹, David Houghton¹, Kate Hallsworth², Djordje G Jakovljevic¹, Michael I Trenell³, Sophie Cassidy⁴

Affiliations

¹ Institute of Cellular Medicine, William Leech Building, Medical School, Newcastle University, Newcastle Upon Tyne, UK.
² Institute of Cellular Medicine, William Leech Building, Medical School, Newcastle University, Newcastle Upon Tyne, UK; The Liver Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
³ NIHR Innovation Observatory, Newcastle University, Newcastle Upon Tyne, UK.
⁴ Institute of Cellular Medicine, William Leech Building, Medical School, Newcastle University, Newcastle Upon Tyne, UK. Electronic address: sophie.cassidy@newcastle.ac.uk.

PMID: 30391504
DOI: 10.1016/j.diabres.2018.10.022

Abstract

Cardiorespiratory fitness (CRF) is impaired in those with metabolic diseases and strongly predicts mortality. We found that adiposity, not glycaemic control or disease type, is the strongest predictor of low CRF in those with metabolic diseases. We discuss how adiposity and metabolic health may relate to outcomes in obesity.

Keywords: Adiposity; Cardiorespiratory fitness; Glycaemic control; Mortality.

MeSH terms

Adiposity / physiology*
Cardiorespiratory Fitness / physiology*
Female
Humans
Male
Metabolic Syndrome / complications*
Metabolic Syndrome / mortality
Middle Aged
Obesity / complications*
Survival Rate

Abstract

MeSH terms

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