Prevalence and antimicrobial susceptibility pattern of Enterococcus species isolated from different clinical samples at Black Lion Specialized Teaching Hospital, Addis Ababa, Ethiopia

BMC Res Notes. 2018 Nov 6;11(1):793. doi: 10.1186/s13104-018-3898-0.

Abstract

Objective: Enterococci which are parts of the normal intestinal flora are opportunistic human pathogens. Their increasing importance is largely due to their resistance to antimicrobials. So the aim this study was to determine the prevalence and antimicrobial pattern of Enterococcus spp.

Result: From the total of 422 samples processed, 15 Enterococcus species were isolated. In this study, linezolid were the drug of choice for Enterococcus species, which showed 100% sensitive followed by vancomycin 93.3% sensitive. In contrast, highly resistance (80%) was observed for ampicillin followed by doxycycline (73.3%). All of isolated Enterococci were sensitive to linezolid, however, resistance was observed to common antibiotics. The presence of multidrug resistant Enterococci in our study should be considered as an alarm for Enterococcal infections.

Keywords: Antibiotic susceptibility; Enterococcus; Nosocomial infection.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Ampicillin / pharmacology
  • Anti-Bacterial Agents / pharmacology*
  • Child
  • Child, Preschool
  • Doxycycline / pharmacology
  • Drug Resistance, Bacterial
  • Enterococcus / isolation & purification*
  • Ethiopia
  • Female
  • Gram-Positive Bacterial Infections / microbiology*
  • Hospitals, Teaching / statistics & numerical data*
  • Humans
  • Infant
  • Linezolid / pharmacology
  • Male
  • Microbial Sensitivity Tests / statistics & numerical data*
  • Middle Aged
  • Prevalence
  • Vancomycin / pharmacology
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Vancomycin
  • Ampicillin
  • Linezolid
  • Doxycycline

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