Four removed kerato-lens lenticles (1 for keratoconus, 1 for aphakia, and 2 for myopia) have been studied histologically. The reasons for removal of the lenticles were poor visual acuity in spite of a satisfactory anatomic result in three cases and epithelialization of the interface in one case. The epithelium presented modifications, particularly with exoserosis of basal cells and irregularities of thickness. The Bowman membrane was irregular and interrupted in some parts. The corneal stroma had few cells; the keratocytes were observed in the periphery of the lenticle and near the interface.