Primary cutaneous embryonal rhabdomyosarcoma with desmoplastic growth pattern and anaplastic lymphoma kinase overexpression. Report of a case with special emphasis on the differential diagnosis

Clin Exp Dermatol. 2019 Oct;44(7):822-824. doi: 10.1111/ced.13877. Epub 2018 Dec 30.

Authors

V Sabater-Marco¹, R Ballester-Sánchez², L Navarro-Cerveró³, C Fuster-Diana⁴, J A García-García¹, R Botella-Estrada⁵

Affiliations

¹ Department of Pathology, University General Hospital, Avenida Tres Cruces 2, 46014, Valencia, Spain.
² Department of Dermatology, Hospital La Plana, Vila-real, Spain.
³ Department of Pathology, Laboratory of Molecular Pathology, University General Hospital, Valencia, Spain.
⁴ Department of Surgery, University General Hospital, Avenida Tres Cruces 2, 46014, Valencia, Spain.
⁵ Department of Dermatology, University Hospital La Fe, Valencia, Spain.

PMID: 30597602
DOI: 10.1111/ced.13877

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Aged
Anaplastic Lymphoma Kinase / metabolism*
Desmin / metabolism
Diagnosis, Differential
Fatal Outcome
Female
Humans
Immunohistochemistry / methods
Keratins / metabolism
Muscle, Smooth / metabolism
MyoD Protein / metabolism
Myogenin / metabolism
Neoplasm Metastasis
Rhabdomyosarcoma, Embryonal / metabolism*
Rhabdomyosarcoma, Embryonal / pathology*
Rhabdomyosarcoma, Embryonal / surgery

Substances

Desmin
MYOG protein, human
MyoD Protein
MyoD1 myogenic differentiation protein
Myogenin
Keratins
Anaplastic Lymphoma Kinase