Chemical Constituents of the Leaves of Peltophorum pterocarpum and Their Bioactivity

Yue-Chiun Li; Ping-Chung Kuo; Mei-Lin Yang; Tzu-Yu Chen; Tsong-Long Hwang; Chih-Chao Chiang; Tran Dinh Thang; Nguyen Ngoc Tuan; Jason T C Tzen

doi:10.3390/molecules24020240

Chemical Constituents of the Leaves of Peltophorum pterocarpum and Their Bioactivity

Molecules. 2019 Jan 10;24(2):240. doi: 10.3390/molecules24020240.

Authors

Yue-Chiun Li¹, Ping-Chung Kuo², Mei-Lin Yang³, Tzu-Yu Chen⁴, Tsong-Long Hwang^{5

6

7}, Chih-Chao Chiang⁸, Tran Dinh Thang^{9

10}, Nguyen Ngoc Tuan¹¹, Jason T C Tzen¹²

Affiliations

¹ Graduate Institute of Biotechnology, National Chung-Hsing University, Taichung 402, Taiwan. ycli0126@gmail.com.
² School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. z10502016@email.ncku.edu.tw.
³ Department of Biotechnology, National Formosa University, Yunlin 632, Taiwan. L3891104@nckualumni.org.tw.
⁴ Department of Biotechnology, National Formosa University, Yunlin 632, Taiwan. black4635@gmail.com.
⁵ Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. htl@mail.cgu.edu.tw.
⁶ Research Center for Industry of Human Ecology, Research Center for Chinese Herbal Medicine, and Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan. htl@mail.cgu.edu.tw.
⁷ Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan. htl@mail.cgu.edu.tw.
⁸ Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. moonlight0604@hotmail.com.
⁹ School of Chemistry, Biology and Environment, Vinh University, Vinh City 43159, Vietnam. thangtd@vinhuni.edu.vn.
¹⁰ NTT Institute of High Technology, Nguyen Tat Thanh University, Ho Chi Minh City 72820, Vietnam. thangtd@vinhuni.edu.vn.
¹¹ Institute of Biotechnology and Food Technology, Industrial University of Ho Chi Minh City, Ho Chi Minh City 71408, Vietnam. nguyenngoctuan@iuh.edu.vn.
¹² Graduate Institute of Biotechnology, National Chung-Hsing University, Taichung 402, Taiwan. tctzen@dragon.nchu.edu.tw.

Abstract

Two new sesquiterpenoids peltopterins A and B (compounds 1 and 2) and fifty-two known compounds were isolated from the methanol extract of P. pterocarpum and their chemical structures were established through spectroscopic and mass spectrometric analyses. The isolates 40, 43, 44, 47, 48, 51 and 52 exhibited potential inhibitory effects of superoxide anion generation or elastase release.

Keywords: Fabaceae; elastase release; sesquiterpenoid; superoxide anion generation.

MeSH terms

Fabaceae / chemistry*
Mass Spectrometry
Molecular Structure
Pancreatic Elastase / metabolism
Plant Extracts / analysis
Plant Leaves / chemistry
Sesquiterpenes / chemistry
Sesquiterpenes / isolation & purification*
Superoxides / metabolism

Substances

Plant Extracts
Sesquiterpenes
Superoxides
Pancreatic Elastase

Abstract

MeSH terms

Substances

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