Think We Understand the Role of DRP1 in Mitochondrial Biology? Zinc Again!

Jerry Edward Chipuk

doi:10.1016/j.molcel.2018.12.024

Think We Understand the Role of DRP1 in Mitochondrial Biology? Zinc Again!

Mol Cell. 2019 Jan 17;73(2):197-198. doi: 10.1016/j.molcel.2018.12.024.

Author

Jerry Edward Chipuk¹

Affiliation

¹ Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; Department of Dermatology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA; The Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA. Electronic address: jerry.chipuk@mssm.edu.

Abstract

In this issue of Molecular Cell, Cho et al. (2019) identify a mechanism by which the mitochondrial division machinery provides selective pressure to identify dysfunctional organelles through the coordinated action of DRP1, Zip1, and Zn²⁺ transport into mitochondria.

Publication types

Comment

MeSH terms

Mitochondria*
Mitochondrial Dynamics
Zinc*

Substances

Zinc

Abstract

Publication types

MeSH terms

Substances

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