[Mechanism of innate immunity and adaptive immunity in the development of allergic rhinitis]

Abstract

The pathogenesis of allergic rhinitis (AR) has not well been clarified, and the imbalance of immune system is its important feature. Interaction between innate and adaptive immune cells and inflammatory mediators secreted by them triggers, maintains and aggravates AR. In this review, Toll-like receptor signaling pathways are used as a bridge to systematically analyze the mechanisms of innate and adaptive immunity in the development of AR.

Keywords: Toll-like receptor; adaptive immunity; allergic,rhinitis; innate immunity.