Launch and preliminary analysis of Hospital de La Princesa's inter-specialists biological therapies unit
Reumatol Clin (Engl Ed). 2019 Mar-Apr;15(2):63-68.
doi: 10.1016/j.reuma.2018.11.008.
Epub 2019 Jan 26.
[Article in
English,
Spanish]
Authors
José María Alvaro-Gracia
1
, Miguel Arredondo
2
, Esteban Daudén
3
, Virginia Meca-Lallana
4
, Alberto Morell
5
, Javier P Gisbert
6
, Guillermo Fernández-Jiménez
2
, Rosario García de Vicuña
7
, Francisco Javier Aspa
8
, María Jesús García de Yébenes
9
, Loreto Carmona
9
Affiliations
- 1 Biologics Therapy Unit, Hospital Universitario de La Princesa, Madrid, Spain; Rheumatology Service, Hospital de La Princesa, Madrid, Spain. Electronic address: jalvarogracia@gmail.com.
- 2 Biologics Therapy Unit, Hospital Universitario de La Princesa, Madrid, Spain; Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain.
- 3 Biologics Therapy Unit, Hospital Universitario de La Princesa, Madrid, Spain; Dermatology Service, Hospital de La Princesa, Madrid, Spain.
- 4 Biologics Therapy Unit, Hospital Universitario de La Princesa, Madrid, Spain; Neurology Service, Hospital de La Princesa, Madrid, Spain.
- 5 Biologics Therapy Unit, Hospital Universitario de La Princesa, Madrid, Spain; Hospital Pharmacy Service, Hospital de La Princesa, Madrid, Spain.
- 6 Biologics Therapy Unit, Hospital Universitario de La Princesa, Madrid, Spain; Gastroenterology Service, Hospital de La Princesa, Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Spain.
- 7 Rheumatology Service, Hospital de La Princesa, Madrid, Spain.
- 8 Medical Direction, Hospital de La Princesa, Madrid, Spain.
- 9 Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain.
Abstract
We herein describe an inter-specialists unit for the monitoring and management of biological therapies and analyze the utilization of biological agents across specialties and diseases. Protocols and therapeutic objectives, as well as outcomes and protocol deviations, are shared and discussed periodically between specialists. All patients treated at one centre with any biological treatment from January 2000 by rheumatology, gastroenterology, dermatology, or neurology, regardless diagnosis, are identified by Clinical Pharmacy and included in an ongoing database that detects use and outcome. The drugs, survival, and reasons for discontinuation differ significantly across specialties. This approach has helped us recognizing the challenges and size of the problem of sharing expensive medications across specialties, and has served as a starting point to contribute to the better use of these compounds.
Keywords:
Biological therapy; Dermatology; Dermatología; Effectiveness; Eficacia; Farmacia; Gastroenterology; Gastroenterología; Neurology; Neurología; Patrones de práctica del médico; Pharmacy; Physician's practice patterns; Protocol; Protocolo; Registries; Registros; Reumatología; Rheumatology; Safety; Seguridad; Terapia biológica.
Copyright © 2018 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.
MeSH terms
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Adult
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Aged
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Benchmarking
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Biological Factors / therapeutic use*
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Biological Therapy*
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Dermatology
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Drug Utilization / statistics & numerical data
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Female
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Gastroenterology
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Hospital Units / organization & administration*
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Hospital Units / statistics & numerical data
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Hospitals, Public / organization & administration
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Hospitals, Public / statistics & numerical data
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Humans
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Interdisciplinary Communication*
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Kaplan-Meier Estimate
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Male
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Middle Aged
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Neurology
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Outcome Assessment, Health Care
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Practice Patterns, Physicians' / statistics & numerical data
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Proportional Hazards Models
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Retrospective Studies
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Rheumatology
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Spain