Coccidioidal Meningitis in New York Traced to Texas by Fungal Genomic Analysis

Clin Infect Dis. 2019 Aug 30;69(6):1060-1062. doi: 10.1093/cid/ciz052.

Abstract

A child developed hydrocephalus. Sixteen months later, it was discovered to be a complication of coccidioidal meningitis. The infection's source was uncertain until genomic analysis of the fungal isolate identified its origin to be a visit to Beeville, Texas. Improved national reporting of cases of coccidioidomycosis might reduce diagnostic delays.

Keywords: Coccidioides; epidemiology; fungal genomics; meningitis; pediatrics.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Biomarkers
  • Coccidioides / genetics*
  • Coccidioidomycosis / diagnosis*
  • Coccidioidomycosis / epidemiology
  • Coccidioidomycosis / microbiology*
  • Contact Tracing
  • Genome, Fungal*
  • Genomics* / methods
  • Humans
  • Infant
  • Male
  • Meningitis, Fungal / diagnosis*
  • Meningitis, Fungal / epidemiology
  • Meningitis, Fungal / microbiology*
  • New York / epidemiology
  • Symptom Assessment
  • Texas / epidemiology

Substances

  • Biomarkers