Gonococcal infection: An unresolved problem
Enferm Infecc Microbiol Clin (Engl Ed). 2019 Aug-Sep;37(7):458-466.
doi: 10.1016/j.eimc.2018.12.008.
Epub 2019 Feb 4.
[Article in
English,
Spanish]
Affiliations
- 1 Unidad de ITS Vall d'Hebron-Drassanes, Servicio de Enfermedades Infecciosas, Hospital Universitario Vall d'Hebron, Barcelona, España; Vall d'Hebron Institut de Recerca, Barcelona, España; Universitat de Barcelona, Barcelona, España; GeITS de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC), Madrid, España.
- 2 Vall d'Hebron Institut de Recerca, Barcelona, España; GeITS de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC), Madrid, España; Servicio de Microbiología, Hospital Universitario Vall d'Hebron, Barcelona, España; Departamento de Genética y Microbiología, Universitat Autònoma de Barcelona, Barcelona, España. Electronic address: juserra@vhebron.net.
Abstract
Gonococcal infection is a current public health problem worldwide, being the second most prevalent bacterial sexually transmitted infection. The etiologic agent is Neisseria gonorrhoeae, a gram-negative diplococcus, and mainly causes urethritis in men. In women up to 50% of infections can be asymptomatic. N. gonorrhoeae has a great ability to develop antibiotic resistance, so the last remaining therapeutic option are extended spectrum cephalosporins. Many guides recommend dual therapy with ceftriaxone and azithromycin, but in recent years the resistance to azithromycin is also increasing, so that dual treatment is being questioned by scientific societies.
Keywords:
Diagnosis; Diagnóstico; Gonococcal infection; Infección gonocócica; Tratamiento; Treatment.
Copyright © 2019 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.
MeSH terms
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Adult
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use
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Child
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Child Abuse, Sexual
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Contact Tracing
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Disease Transmission, Infectious / prevention & control
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Drug Resistance, Multiple, Bacterial
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Drug Therapy, Combination
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Female
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Global Health
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Gonorrhea / congenital
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Gonorrhea / drug therapy*
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Gonorrhea / epidemiology
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Gonorrhea / transmission
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Humans
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Infant, Newborn
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Infectious Disease Transmission, Vertical / prevention & control
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Male
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Neisseria gonorrhoeae / drug effects*
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Ophthalmia Neonatorum / drug therapy
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Ophthalmia Neonatorum / epidemiology
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Ophthalmia Neonatorum / microbiology
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Pregnancy
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Pregnancy Complications, Infectious / microbiology
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Sexual Behavior
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Urethritis / drug therapy
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Urethritis / epidemiology
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Urethritis / microbiology
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Uterine Cervicitis / drug therapy
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Uterine Cervicitis / epidemiology
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Uterine Cervicitis / microbiology