Enormous Aneurysm in Coronary Artery Fistula With Immunoglobulin G4-Related Disease

Can J Cardiol. 2019 Feb;35(2):230.e1-230.e3. doi: 10.1016/j.cjca.2018.11.030. Epub 2018 Dec 5.

Abstract

We report the first case of coronary artery fistula with aneurysmal change in a patient with immunoglobulin G4-related disease (IgG4-RD). This case revealed concomitant coronary artery dilation, pericardial inflammatory nodules, and coronary-pulmonary fistula aneurysm in addition to several IgG4-RD lesions. Each of these features was located in close proximity to the thickened pericardium. These lesions might result from inflammation of the pericardial space, which extended to the coronary-pulmonary artery vessels, leading to aneurysmal formation. This case will enhance our understanding of the pathological mechanisms of IgG4-RD inflammation.

Publication types

  • Case Reports

MeSH terms

  • Aneurysm / diagnosis
  • Aneurysm / etiology*
  • Arteriovenous Fistula / complications*
  • Arteriovenous Fistula / diagnosis
  • Computed Tomography Angiography
  • Coronary Angiography
  • Coronary Artery Disease / diagnosis
  • Coronary Artery Disease / etiology*
  • Coronary Vessels / diagnostic imaging*
  • Humans
  • Immunoglobulin G / blood*
  • Immunoglobulin G / immunology
  • Immunoglobulin G4-Related Disease / complications*
  • Immunoglobulin G4-Related Disease / diagnosis
  • Immunoglobulin G4-Related Disease / immunology
  • Male
  • Middle Aged
  • Positron-Emission Tomography

Substances

  • Immunoglobulin G