Renal medullary carcinoma in a young mixed-race man in Japan

Pathol Int. 2019 Apr;69(4):241-245. doi: 10.1111/pin.12783. Epub 2019 Mar 7.

Abstract

Renal medullary carcinoma (RMC) is a rare and aggressive cancer associated with the sickle cell trait. The diagnosis of RMC depends on recognition of its histologic features and immunohistochemical deficiency of INI1, but correct diagnosis is sometimes difficult, especially if a patient's information on race, past, and family medical history is unclear. At present, this is the first report on RMC in Japan.

Keywords: carcinoma; kidney; medullary; sickle cell trait.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma, Medullary / diagnostic imaging*
  • Carcinoma, Medullary / genetics
  • Carcinoma, Medullary / pathology
  • Carcinoma, Renal Cell / diagnostic imaging*
  • Carcinoma, Renal Cell / genetics
  • Carcinoma, Renal Cell / pathology
  • Diagnosis, Differential
  • Humans
  • Immunohistochemistry
  • Japan
  • Kidney Neoplasms / diagnostic imaging*
  • Kidney Neoplasms / genetics
  • Kidney Neoplasms / pathology
  • Male
  • SMARCB1 Protein / metabolism
  • Sickle Cell Trait / diagnostic imaging*
  • Sickle Cell Trait / pathology
  • Tomography, X-Ray Computed
  • Young Adult

Substances

  • SMARCB1 Protein
  • SMARCB1 protein, human