Whole-exome sequencing identified novel mutations in FGA and FGG genes in the patients with decreased fibrinogen

Thromb Res. 2019 May:177:79-82. doi: 10.1016/j.thromres.2019.03.002. Epub 2019 Mar 5.

Authors

Zheng Cao¹, Ying Dong¹, Jiazi Zeng¹, Hongyuan Zhu¹, Xin Xie¹, Jingrui Liu¹, Yanhong Zhai¹, Lin Li²

Affiliations

¹ Department of Laboratory Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Chaoyang, Beijing 100026, China.
² Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Chaoyang, Beijing 100026, China. Electronic address: linlithu@163.com.

PMID: 30856382
DOI: 10.1016/j.thromres.2019.03.002

No abstract available

Keywords: Congenital dysfibrinogenemia; FGA; FGG; Whole-exome sequencing.

Publication types

Case Reports
Letter

MeSH terms

Afibrinogenemia / congenital
Afibrinogenemia / genetics*
Exome Sequencing
Female
Fibrinogen / genetics*
Humans
Mutation

Substances

FGA protein, human
FGB protein, human
FGG protein, human
Fibrinogen