In vitro and in vivo hemocompatibility assessment of ultrathin sulfobetaine polymer coatings for silicon-based implants

J Biomater Appl. 2019 Aug;34(2):297-312. doi: 10.1177/0885328219831044. Epub 2019 Mar 12.
No abstract available

Keywords: Sulfobetaine; blood compatibility; microelectromechanical systems; non-fouling surface modifications; silicon nanopore membrane; ultrathin brush polymer; zwitterionic polymer.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Biofouling / prevention & control
  • Blood / metabolism
  • Blood Coagulation / drug effects
  • Coated Materials, Biocompatible / chemistry*
  • Coated Materials, Biocompatible / metabolism
  • Female
  • Humans
  • Membranes, Artificial
  • Methacrylates / chemical synthesis*
  • Methacrylates / metabolism
  • Models, Animal
  • Molecular Conformation
  • Nanoparticles / chemistry*
  • Nanoparticles / metabolism
  • Platelet Adhesiveness / drug effects
  • Porosity
  • Prostheses and Implants
  • Silicon / chemistry*
  • Silicon / metabolism
  • Surface Properties
  • Swine
  • Time Factors

Substances

  • Coated Materials, Biocompatible
  • Membranes, Artificial
  • Methacrylates
  • sulfobetaine methacrylate polymer
  • Silicon