Relevance of the drug-drug interactions between lidocaine and the pharmacokinetic enhancers ritonavir and cobicistat

AIDS. 2019 May 1;33(6):1100-1102. doi: 10.1097/QAD.0000000000002162.

Authors

Bart G J Dekkers¹, Wouter F W Bierman², Daan J Touw^{1

3}, Jan-Willem C Alffenaar¹

Affiliations

¹ Department of Clinical Pharmacy and Pharmacology.
² Department of Internal Medicine - Infectious Diseases, University Medical Center Groningen.
³ Department of Pharmacokinetics, Toxicology and Targeting, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Anesthetics, Local / administration & dosage
Anesthetics, Local / pharmacokinetics*
Anti-Bacterial Agents / administration & dosage
Anti-HIV Agents / administration & dosage*
Chromatography, Liquid
Cobicistat / administration & dosage*
Drug Interactions*
HIV Infections / complications
HIV Infections / drug therapy
Humans
Injections, Intramuscular
Lidocaine / administration & dosage
Lidocaine / pharmacokinetics*
Male
Middle Aged
Penicillin G / administration & dosage
Ritonavir / administration & dosage*
Serum / chemistry
Syphilis / drug therapy
Tandem Mass Spectrometry

Substances

Anesthetics, Local
Anti-Bacterial Agents
Anti-HIV Agents
Lidocaine
Cobicistat
Ritonavir
Penicillin G