FLT3N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

Leukemia. 2019 Sep;33(9):2310-2314. doi: 10.1038/s41375-019-0465-1. Epub 2019 Apr 5.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antigens, CD34 / genetics
  • Carcinogenesis / genetics*
  • Gene Rearrangement / genetics
  • Heterografts
  • Histone-Lysine N-Methyltransferase / genetics*
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Mice
  • Mice, Inbred NOD
  • Myeloid-Lymphoid Leukemia Protein / genetics*
  • Nuclear Proteins / genetics*
  • fms-Like Tyrosine Kinase 3 / genetics*

Substances

  • Antigens, CD34
  • KMT2A protein, human
  • MLLT3 protein, human
  • Nuclear Proteins
  • Myeloid-Lymphoid Leukemia Protein
  • Histone-Lysine N-Methyltransferase
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3