Evaluation of pain, swelling and trismus after extraction of impacted third molars relative to the use of betamethasone in submucusal infiltration

J Biol Regul Homeost Agents. 2019 Jan-Feb;33(1 Suppl. 1):9-17.

Abstract

The aim of this study was to evaluate the anti-inflammatory effect of a single 4 mg injection of submucosal betamethasone after extraction of impacted third molars. Single-centre, single-blinded, parallel group study; Forty-three patients were submitted to impacted third molar extraction. In this study, 4 mg single-dose submucosal betamethasone was injected in the interventional group, while in the control group nothing was injected. Postoperative measurement included pain via the VAS scale, swelling and trismus with facial measurements and maximum mouth openings, and finally nerve sensitivity. There was a significant difference between the two groups regarding trismic pain and edema. The use of a single 4 mg submucosal betamethasone injection leads to a reduction of oedema, trismus and pain in patients undergoing impacted third molar extraction. .

Keywords: betamethasone; corticosteroids; third molar extraction.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Betamethasone / therapeutic use
  • Edema / drug therapy
  • Edema / etiology
  • Humans
  • Molar, Third* / surgery
  • Pain Measurement
  • Pain, Postoperative / drug therapy
  • Pain, Postoperative / etiology
  • Prospective Studies
  • Tooth Extraction / adverse effects
  • Tooth, Impacted* / surgery
  • Trismus / etiology

Substances

  • Anti-Inflammatory Agents
  • Betamethasone