POEMS syndrome is a rare multisystemic disease characterised by the coexistence of two main symptoms, polyneuropathy and monoclonal gammopathy, associated with minor symptoms such as organomegaly, endocrinopathy, and skin changes. We describe a patient who presented with symptoms and signs fulfilling the criteria of POEMS. We have carried out a literature review with particular emphasis on its demographic and polymorphic clinical features.
Keywords: Castleman’s disease; POEMS; VEGF; calciphylaxis; monoclonal gammopathy.
Copyright by Società Italiana di Nefrologia SIN, Rome, Italy.