Nose-to-brain delivery of biologics

Ther Deliv. 2019 Apr;10(4):207-210. doi: 10.4155/tde-2019-0013.

Abstract

Graphical abstract.

Keywords: CNS drug delivery; intranasal drug administration-biologics; nanocarriers; nose-to-brain delivery; olfactory epithelium; transport mechanisms.

Publication types

  • Editorial

MeSH terms

  • Administration, Intranasal
  • Biological Products / administration & dosage*
  • Biological Products / pharmacokinetics
  • Blood-Brain Barrier / metabolism
  • Brain / metabolism
  • Brain / physiopathology
  • Brain Diseases / drug therapy*
  • Brain Diseases / physiopathology
  • Drug Delivery Systems*
  • Humans
  • Tissue Distribution

Substances

  • Biological Products