Management of Dysphagia in Patients with Parkinson's Disease and Related Disorders

Intern Med. 2020 Jan 1;59(1):7-14. doi: 10.2169/internalmedicine.2373-18. Epub 2019 Apr 17.

Abstract

Various methods of rehabilitation for dysphagia have been suggested through the experience of treating stroke patients. Although most of these patients recover their swallowing function in a short period, dysphagia in Parkinson's disease (PD) and Parkinson-related disorder (PRD) degenerates with disease progression. Muscle rigidity and bradykinesia are recognized as causes of swallowing dysfunction, and it is difficult to easily apply the strategies for stroke to the rehabilitation of dysphagia in PD patients. Disease severity, weight loss, drooling, and dementia are important clinical predictors. Silent aspiration is a pathognomonic sign that may lead to aspiration pneumonia. Severe PD patients need routine video fluoroscopy or video endoscopy to adjust their food and liquid consistency. Patients with PRD experience rapid progression of swallowing dysfunction. Nutrition combined with nasogastric tube feeding or percutaneous endoscopic gastrostomy feeding should be considered owing to the increased risk of aspiration and difficulty administrating oral nutrition.

Keywords: Parkinson's disease; Parkinson-related disorder; aspiration pneumonia; dysphagia; video endoscopy; video fluoroscopy.

Publication types

  • Review

MeSH terms

  • Deglutition / physiology
  • Deglutition Disorders / diagnosis
  • Deglutition Disorders / etiology
  • Deglutition Disorders / rehabilitation*
  • Disease Progression
  • Enteral Nutrition / methods
  • Humans
  • Hypokinesia / physiopathology
  • Muscle Rigidity / physiopathology
  • Parkinson Disease / complications
  • Parkinson Disease / physiopathology
  • Parkinson Disease / rehabilitation*
  • Pneumonia, Aspiration / prevention & control
  • Respiratory Aspiration / prevention & control*
  • Stroke Rehabilitation