Energy yield (EY) modelling is an indispensable tool to minimize payback time of emerging perovskite-based multi-junction photovoltaics (PV) but it relies on many assumptions about device architecture and environmental conditions. Here, we propose a comprehensive framework that enables rapid simulation of complex architectures of perovskite-based multi-junction PV and detailed calculation of their power output under realistic irradiation conditions in various climatic zones. Applying the framework to perovskite/silicon multi-junction solar modules, we showcase the impact of tracking on energy losses arising from spectral variations. Moreover, we demonstrate the strong dependency of the EY of bifacial multi-junction solar modules on the albedo.