Effect of Cannabis Use on Human Immunodeficiency Virus DNA During Suppressive Antiretroviral Therapy

Antoine Chaillon; Masato Nakazawa; Christy Anderson; Aaron Christensen-Quick; Ronald J Ellis; Donald Franklin; Sheldon R Morris; Sara Gianella

doi:10.1093/cid/ciz387

Effect of Cannabis Use on Human Immunodeficiency Virus DNA During Suppressive Antiretroviral Therapy

Clin Infect Dis. 2020 Jan 1;70(1):140-143. doi: 10.1093/cid/ciz387.

Authors

Antoine Chaillon¹, Masato Nakazawa¹, Christy Anderson¹, Aaron Christensen-Quick¹, Ronald J Ellis², Donald Franklin^{2

3}, Sheldon R Morris¹, Sara Gianella¹

Affiliations

¹ The Division of Infectious Diseases and Global Public Health, San Diego, La Jolla.
² Department of Neurosciences, University of California, San Diego, La Jolla.
³ Department of Psychiatry, University of California, San Diego, La Jolla.

Abstract

Cannabis use is frequent among people living with human immunodeficiency virus (HIV) and is associated with reduced systemic inflammation. We observed a faster HIV DNA decay during antiretroviral therapy among cannabis users, compared to those with no drug use. No cannabis effect was observed on cellular HIV RNA transcription.

Keywords: HIV DNA; MSM; cannabis; cellular transcription.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Cannabis* / adverse effects
DNA
HIV
HIV Infections* / complications
HIV Infections* / drug therapy
Humans
Substance-Related Disorders*

Substances

DNA

Abstract

Publication types

MeSH terms

Substances

Grants and funding