Ultrasonographic Evidence of Predominance of Acute Extracapsular and Chronic Intrasynovial Patterns in 100 Cases of Psoriatic Hand Dactylitis

J Rheumatol. 2020 Feb;47(2):227-233. doi: 10.3899/jrheum.190046. Epub 2019 May 15.

Abstract

Objective: To use ultrasonography to study whether the duration of psoriatic dactylitis was associated with different patterns of extracapsular and synovial-based involvement.

Methods: One hundred cases of hand dactylitis from 85 patients with psoriatic arthritis (PsA) were consecutively enrolled in a multicenter cross-sectional study and divided into 2 groups according to dactylitis duration (shorter or longer than the median: 20 weeks). All dactylitis fingers were investigated using high-frequency ultrasound both in greyscale (GS) and power Doppler (PD), evaluating the presence of flexor tenosynovitis, soft tissue edema, subcutaneous PD signal (PDS), extensor tendon involvement, and joint synovitis.

Results: Cases with a shorter dactylitis duration (< 20 weeks) had a significantly higher prevalence of GS flexor tenosynovitis of grade > 2, PD flexor tenosynovitis, soft tissue edema, and subcutaneous PDS (p = 0.001, p < 0.001, p < 0.05, and p = 0.001, respectively). However, the presence of synovitis in GS and PD mode (in both cases at proximal interphalangeal level) was more frequent in patients with longer dactylitis duration (p < 0.001). When detected in the chronic form, flexor tenosynovitis was grade 2 or lower.

Conclusion: In a large cohort of PsA hand dactylitis, we found a predominant extracapsular inflammation (flexor tenosynovitis and soft tissue edema) in early cases and a high prevalence of joint synovitis at proximal interphalangeal level in the chronic form. However, longitudinal imaging studies are needed to clarify these aspects.

Keywords: DACTYLITIS; EDEMA; FLEXOR TENDON; PSORIATIC ARTHRITIS; TENOSYNOVITIS; ULTRASOUND.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Arthritis, Psoriatic / complications*
  • Arthritis, Psoriatic / diagnostic imaging*
  • Arthritis, Psoriatic / epidemiology
  • Cohort Studies
  • Cross-Sectional Studies
  • Edema / complications
  • Edema / diagnostic imaging
  • Edema / epidemiology
  • Female
  • Finger Joint / diagnostic imaging*
  • Hand / diagnostic imaging*
  • Humans
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Synovitis / complications*
  • Synovitis / diagnostic imaging*
  • Synovitis / epidemiology
  • Tendons / diagnostic imaging
  • Tenosynovitis / complications*
  • Tenosynovitis / diagnostic imaging*
  • Tenosynovitis / epidemiology
  • Ultrasonography, Doppler / methods*