CD40-targeted peptide proposed for type 1 diabetes therapy lacks relevant binding affinity to its cognate receptor
Diabetologia
.
2019 Sep;62(9):1727-1729.
doi: 10.1007/s00125-019-4893-2.
Epub 2019 May 17.
Authors
Philippe P Pagni
1
,
Anitra Wolf
1
,
Mauro Lo Conte
1
,
Ronald Yeh
1
,
Guangsen Fu
1
,
Fa Liu
1
,
Matthias von Herrath
1
,
Ken Coppieters
2
Affiliations
1
Novo Nordisk Research Center, Seattle, WA, USA.
2
Novo Nordisk A/S Research Projects, Novo Nordisk Park, DK-2760, Måløv, Denmark. kncp@novonordisk.com.
PMID:
31101931
DOI:
10.1007/s00125-019-4893-2
No abstract available
Keywords:
CD40; CD40L; Type 1 diabetes.
Publication types
Letter
Comment
MeSH terms
Animals
CD40 Antigens
CD40 Ligand
Diabetes Mellitus, Type 1*
Mice
Mice, Inbred NOD
Peptides
Substances
CD40 Antigens
Peptides
CD40 Ligand