Variation in a novel antipseudomonal antimicrobial consumption metric across hospital inpatient units at a Veterans Affairs hospital: A retrospective cohort study

Am J Infect Control. 2019 Oct;47(10):1263-1264. doi: 10.1016/j.ajic.2019.04.170. Epub 2019 May 30.

Abstract

A novel antimicrobial consumption metric designed to identify the proportion of carbapenem consumption (PoCC) among broad-spectrum antipseudomonal antimicrobials has been shown to vary significantly by US Census Bureau region. This retrospective surveillance study identified significant total PoCC variability (27%; P = .001) across 8 inpatient units from January 2017 through June 2018. This metric may be useful in identifying and comparing inpatient units that may be overusing antipseudomonal carbapenems.

Keywords: Antimicrobial stewardship; Antimicrobial use metrics; Carbapenem.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Antimicrobial Stewardship / methods
  • Carbapenems / therapeutic use
  • Drug Utilization
  • Hospital Units
  • Hospitals
  • Humans
  • Inpatients
  • Microbial Sensitivity Tests / methods
  • Pseudomonas aeruginosa / drug effects*
  • Retrospective Studies
  • Veterans

Substances

  • Anti-Bacterial Agents
  • Carbapenems