One-bloc percutaneous large biopsy of soft-tissue tumours: feasibility study and possible indications

Clin Radiol. 2019 Aug;74(8):649.e11-649.e17. doi: 10.1016/j.crad.2019.05.004. Epub 2019 Jun 6.

Abstract

Aim: To report the early results of the Intact lesion excision system (LES) regarding feasibility, tolerance and efficiency in obtaining soft-tissue tumour samples under ultrasound guidance.

Materials and methods: The feasibility and tolerance of Intact LES procedures under ultrasound guidance were studied prospectively in 15 patients. The procedure was performed on an outpatient basis under local anaesthesia by a single interventional radiologist with 6 years of experience and lasted around 30 min.

Results: The feasibility of the Intact LES for soft-tissue masses was good except when lesions were hard and calcified. Tolerance was good, with median pain experienced during the procedure evaluated at 4.5/10 (SD 2.2) and median post-procedural pain at day 1 evaluated at 1.8/10 (SD 2.5). No major complications were observed; however, for vascularised lesions, one case of acute wound bleeding and two post-procedural haematomas led to delayed pain.

Conclusion: Percutaneous biopsy of suspected soft-tissue sarcoma using the LES device under ultrasound guidance is well tolerated and feasible. After a first non-contributing core biopsy, and especially, in the case of lipomatous lesions, it is a valuable option to consider, as is surgical incision biopsy.

MeSH terms

  • Adult
  • Aged
  • Biopsy, Large-Core Needle
  • Feasibility Studies
  • Female
  • Humans
  • Image-Guided Biopsy
  • Male
  • Middle Aged
  • Prospective Studies
  • Sarcoma / diagnostic imaging*
  • Sarcoma / pathology*
  • Soft Tissue Neoplasms / diagnostic imaging*
  • Soft Tissue Neoplasms / pathology*
  • Ultrasonography, Interventional / methods*
  • Young Adult