Use of Tachosil® as an adjuvant therapeutic option in neurotrophic keratopathy in order to prevent perforation

Indian J Ophthalmol. 2019 Jul;67(7):1198-1200. doi: 10.4103/ijo.IJO_1573_18.

Abstract

We present two cases of women who suffered from neurotrophic keratopathy (one of them had undergone penetrating keratoplasty) which had led to corneal thinning. Tachosil® was used as an adjuvant treatment after topical medication by itself failed in both cases. To our knowledge, there are no reported cases of the use of Tachosil® in corneal grafts.

Keywords: Corneal graft; Tachosil®; corneal ulcer; neurotrophic keratopathy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Corneal Perforation / prevention & control*
  • Corneal Ulcer / pathology
  • Corneal Ulcer / therapy*
  • Cranial Nerve Diseases / pathology
  • Cranial Nerve Diseases / therapy*
  • Drug Combinations
  • Female
  • Fibrinogen / therapeutic use*
  • Humans
  • Keratoplasty, Penetrating
  • Ophthalmic Nerve / pathology*
  • Surgical Sponges*
  • Thrombin / therapeutic use*

Substances

  • Drug Combinations
  • TachoSil
  • Fibrinogen
  • Thrombin