When Statins Cause an Autoimmune Response: A Report of a Severe Case of Rhabdomyolysis

Am J Med. 2020 Jan;133(1):50-51. doi: 10.1016/j.amjmed.2019.05.043. Epub 2019 Jun 24.

Authors

Seba Hasan¹, Ashraf Abushahin², Richard Prayson³, Ahmad Kilani²

Affiliations

¹ Department of Internal Medicine, Cleveland Clinic Foundation, Ohio. Electronic address: hasans@ccf.org.
² Department of Internal Medicine, Cleveland Clinic Foundation, Ohio.
³ Anatomic Pathology, Cleveland Clinic Foundation, Ohio.

PMID: 31247184
DOI: 10.1016/j.amjmed.2019.05.043

No abstract available

Publication types

Case Reports

MeSH terms

Aged
Atorvastatin / adverse effects*
Autoantibodies / immunology
Autoimmune Diseases / blood
Autoimmune Diseases / chemically induced*
Autoimmune Diseases / immunology
Autoimmune Diseases / therapy
Azathioprine / therapeutic use
Creatine Kinase / blood
Humans
Hydroxymethylglutaryl CoA Reductases / immunology
Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects*
Immunoglobulins, Intravenous / therapeutic use
Immunologic Factors / therapeutic use
Male
Muscle, Skeletal / immunology
Muscle, Skeletal / pathology*
Muscular Diseases / blood
Muscular Diseases / chemically induced
Muscular Diseases / immunology
Muscular Diseases / therapy
Myoglobin / blood
Necrosis
Prednisone / therapeutic use
Rhabdomyolysis / blood
Rhabdomyolysis / chemically induced*
Rhabdomyolysis / immunology
Rhabdomyolysis / therapy
Severity of Illness Index

Substances

Autoantibodies
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Immunoglobulins, Intravenous
Immunologic Factors
Myoglobin
Atorvastatin
Hydroxymethylglutaryl CoA Reductases
Creatine Kinase
Azathioprine
Prednisone