Potential use of microarray patches for vaccine delivery in low- and middle- income countries

Vaccine. 2019 Jul 26;37(32):4427-4434. doi: 10.1016/j.vaccine.2019.03.035. Epub 2019 Jun 28.

Abstract

Microarray patches (MAPs), also referred to as microneedle patches, are a novel methodology that have the potential to overcome barriers to vaccine delivery in low- and middle-income countries (LMICs), and transform the way that vaccines are delivered within immunization programs. The World Health Organization's Initiative for Vaccine Research and its partners are working to understand how MAPs could ease vaccine delivery and increase equitable access to vaccines in LMICs. Global stakeholders have been engaged to evaluate technical, economic, and programmatic challenges; to validate assumptions where possible; and to propose areas of focus to facilitate future vaccine-MAP product development. This report summarizes those learnings.

Keywords: Delivery; Microarray patches; Microneedle patches; Product development; Vaccine.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Developing Countries
  • Drug Delivery Systems / methods*
  • Humans
  • Immunization Programs / methods
  • Needles
  • Vaccination / methods*
  • Vaccines / administration & dosage*
  • Vaccines / immunology*

Substances

  • Vaccines