Oxygen-Mediated Control of the Keratinocyte Proliferation-Differentiation Axis

J Invest Dermatol. 2020 Jan;140(1):235-238.e3. doi: 10.1016/j.jid.2019.05.030. Epub 2019 Jul 5.

Authors

Rosita Koh¹, Ildikó Szeverényi², Bernett Lee³, Simon L I J Denil⁴, Soon Yew John Lim⁴, Paula A Benny², Nicolas Grasset², Bien-Keem Tan⁵, E Birgitte Lane⁶

Affiliations

¹ Skin Research Institute of Singapore, Singapore; Institute of Medical Biology, Singapore.
² Institute of Medical Biology, Singapore.
³ Singapore Immunology Network, Singapore.
⁴ Skin Research Institute of Singapore, Singapore.
⁵ Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Singapore.
⁶ Skin Research Institute of Singapore, Singapore; Institute of Medical Biology, Singapore. Electronic address: birgit.lane@sris.a-star.edu.sg.

PMID: 31283927
DOI: 10.1016/j.jid.2019.05.030

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Proliferation
Cells, Cultured
Cluster Analysis
Filaggrin Proteins
Gene Expression Regulation
Humans
Hypoxia / metabolism*
Hypoxia / pathology
Hypoxia-Inducible Factor 1, alpha Subunit / genetics
Hypoxia-Inducible Factor 1, alpha Subunit / metabolism*
Interleukin-1 / genetics
Intermediate Filament Proteins / genetics
Keratin-10 / genetics
Keratinocytes / physiology*
Oxygen / metabolism*
Primary Cell Culture
Protein Precursors / genetics
Skin Physiological Phenomena*

Substances

Filaggrin Proteins
HIF1A protein, human
Hypoxia-Inducible Factor 1, alpha Subunit
Interleukin-1
Intermediate Filament Proteins
Protein Precursors
Keratin-10
involucrin
Oxygen