Brugada pattern: a comprehensive review on the demographic and clinical spectrum

BMJ Case Rep. 2019 Jul 11;12(7):e229829. doi: 10.1136/bcr-2019-229829.

Abstract

A prominent coved or saddle-shaped ST-segment elevation followed by T wave changes in V1-V3 and in the absence of other identifiable cause is termed as Brugada pattern. This pattern in the presence of documented ventricular arrhythmias or its symptoms (syncope, seizure) or significant family for sudden cardiac death or abovementioned ECG changes is called Brugada syndrome. Here we present a comprehensive literature review on the precipitation factors of Brugada syndrome/pattern by various stimuli, its presentation, associations, management and outcomes. We are also presenting a unique case of Brugada pattern where the patient's Brugada pattern was unmasked at an extreme old age by infection.

Keywords: arrhythmias; cardiovascular medicine.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged, 80 and over
  • Brugada Syndrome / diagnosis*
  • Brugada Syndrome / therapy
  • Chest Pain / etiology*
  • Electrocardiography
  • Fibrin Fibrinogen Degradation Products / metabolism*
  • Humans
  • Hypoxia / etiology*
  • Hypoxia / physiopathology
  • Male
  • Parkinson Disease / physiopathology*
  • Patient Comfort

Substances

  • Fibrin Fibrinogen Degradation Products
  • fibrin fragment D