Abstract
We implemented subgenomic and whole-genome sequencing to support the investigation of a large hepatitis A virus outbreak among persons experiencing homelessness, users of illicit drugs, or both in California, USA, during 2017-2018. Genotyping data helped confirm case-patients, track chains of transmission, and monitor the effectiveness of public health control measures.
Keywords:
California; United States; genotyping; hepatitis A virus; outbreak; public health; viruses.
Publication types
-
Historical Article
-
Research Support, Non-U.S. Gov't
MeSH terms
-
California / epidemiology
-
Disease Outbreaks
-
Genotype
-
Hepatitis A / epidemiology*
-
Hepatitis A / history
-
Hepatitis A / transmission
-
Hepatitis A / virology*
-
Hepatitis A virus / classification*
-
Hepatitis A virus / genetics*
-
Hepatitis A virus / immunology
-
Hepatitis A virus / isolation & purification
-
History, 21st Century
-
Humans
-
Molecular Typing*
-
Public Health Surveillance
-
Viral Proteins / genetics
-
Whole Genome Sequencing