First Case Report of Maturity-Onset Diabetes of the Young Type 4 Pedigree in a Chinese Family

Mingqun Deng; Xinhua Xiao; Liyuan Zhou; Tong Wang

doi:10.3389/fendo.2019.00406

First Case Report of Maturity-Onset Diabetes of the Young Type 4 Pedigree in a Chinese Family

Front Endocrinol (Lausanne). 2019 Jul 3:10:406. doi: 10.3389/fendo.2019.00406. eCollection 2019.

Authors

Mingqun Deng¹, Xinhua Xiao¹, Liyuan Zhou¹, Tong Wang¹

Affiliation

¹ Key Laboratory of Endocrinology, Department of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Diabetes Research Center of Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.

Abstract

Maturity-onset diabetes of the young (MODY) is the most common monogenetic diabetes, which is easily misdiagnosed. We describe the first Chinese MODY4 family with a novel mutation, indicating that MODY4 cannot be excluded in early-onset obese diabetes, and pancreatic exocrine dysfunction could be present in MODY4.

Keywords: Chinese; MODY4; PDX1; obese; pancreatic exocrine dysfunction.

Publication types

Case Reports