Biochemistry, Myoglobin

Book
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Excerpt

Myoglobin is a protein located primarily in the striated muscles of vertebrates. MB is the gene encoding myoglobin in humans. It encodes a single polypeptide chain with one oxygen binding site. Myoglobin contains a heme prosthetic group that can reversibly bind to oxygen. The body uses it as an oxygen storage protein in muscle. It is able to bind and release oxygen depending on the oxygen concentration in the cell. Its primary function, as a result, is to supply oxygen to myocytes. Myoglobin also functions in the hemostasis of nitric oxide. It additionally plays a role in the detoxification of reactive oxygen species. Myoglobin is the reason for the red color of the muscle of most vertebrates.

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