HIV and Chagas Disease Coinfection, a Tractable Disease?

Betiana Guidetto; Melisa Tatta; Veronica Latini; Milene Gonzales; Adelina Riarte; Silvina Tavella; Eduardo Warley; Javier Altclas

doi:10.1093/ofid/ofz307

HIV and Chagas Disease Coinfection, a Tractable Disease?

Open Forum Infect Dis. 2019 Jul 1;6(7):ofz307. doi: 10.1093/ofid/ofz307.

Authors

Betiana Guidetto¹, Melisa Tatta¹, Veronica Latini¹, Milene Gonzales¹, Adelina Riarte², Silvina Tavella³, Eduardo Warley³, Javier Altclas⁴

Affiliations

¹ Department of Infectious Diseases, Sanatorio de la Trinidad Mitre, CABA, Argentina.
² Department of Parasitology, Instituto Nacional de Parasitologia Dr. Mario Fatala Chaben, CABA, Argentina.
³ Department of Infectious Diseases, Hospital Dr. Diego Paroissien, Buenos Aires, Argentina.
⁴ Department of Infectious Diseases, Sanatorio de la Trinidad Mitre and Sanatorio Anchorena, CABA, Argentina.

Abstract

We present 2 patients born in Argentina who were newly diagnosed with advanced HIV disease and Chagas disease reactivation with central nervous system involvement. The patients received concurrent benznidazole treatment and antiretroviral therapy, showing good response. Improvement in morbidity and mortality due to early treatment makes this treatment appropriate for coinfected patients.

Keywords: Chagas disease; HIV; benznidazole; coinfection; treatment.