Near-infrared fluorescence angiography for intra-operative assessment of pedicled omentoplasty for filling of a pelvic cavity: a pilot study

Tech Coloproctol. 2019 Aug;23(8):723-728. doi: 10.1007/s10151-019-02048-0. Epub 2019 Aug 21.

Abstract

Background: During creation of a pedicled omentoplasty, blood flow to segments of the omentum might become compromised. If unrecognized, this can lead to omental necrosis. The purpose of this study was to investigate the potential added intra-operative value of the use of fluorescence angiography (FA) with indocyanine green (ICG) to assess omental perfusion.

Methods: All consecutive patients undergoing a pedicled omentoplasty in a 6-month period (April 1 2018-October 1 2018) in a University hospital were included. The primary outcome was change in management due to FA. Secondary outcomes included the amount of additionally resected omentum, added surgical time, and quantitative fluorescent values (time to fluorescent enhancement, contrast quantification).

Results: Fifteen patients had pelvic surgery with omentoplasty and FA. Change in management occurred in 12 patients (80%) and consisted of resecting a median of 44 g (range 12-198 g) of poorly perfused omental areas that were not visible by conventional white light. The median added surgical time for the use of FA and subsequent management was 8 min (range 3-39 min). The first fluorescent signal in the omental tissue appeared after a median of 20 s (range 9-37 s) after injection of ICG. The median signal-to-baseline ratio was 23.7 (interquartile range 12.2-29.7) in well perfused and 2.5 (interquartile range 1.7-4.0) in poorly perfused tissue.

Conclusions: FA of a pedicled omentoplasty allows a real-time assessment of omental perfusion and leads to change in management in 80% of the cases in this pilot study. These findings support the conduct of larger studies to determine the impact on patient outcome in this setting.

Keywords: Fluorescence angiography; Indocyanine green (ICG); Omentoplasty; Pelvic filling; Rectal surgery.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Coloring Agents
  • Female
  • Fluorescein Angiography / methods*
  • Humans
  • Indocyanine Green
  • Infrared Rays*
  • Male
  • Middle Aged
  • Monitoring, Intraoperative / methods*
  • Omentum / blood supply*
  • Omentum / diagnostic imaging
  • Omentum / surgery
  • Pelvis / surgery
  • Peritoneal Diseases / diagnostic imaging
  • Peritoneal Diseases / surgery*
  • Pilot Projects
  • Retrospective Studies
  • Young Adult

Substances

  • Coloring Agents
  • Indocyanine Green