Abstract
Ectopic pituitary adenoma is a rare entity that is most commonly located in the sphenoid sinus. We report a case of a patient with ectopic pituitary adenoma with no functional expression associated with empty sella turcica, which gives rise to a broad differential diagnosis. Although it is a benign neoplasm, necrosis is encountered in a proportion of cases. Magnetic resonance imaging is the diagnostic method of choice for hypothalamic-pituitary-related endocrine diseases with endoscopic biopsy for histological confirmation. It is important to include pituitary markers in the immunohistochemical diagnostic panel.
Keywords:
Adenoma hipofisario ectópico; Ectopic pituitary adenoma; Empty pituitary sella turcica; Silla turca vacía; Sphenoidal tumor; Tumor esfenoidal.
Copyright © 2018 Sociedad Española de Anatomía Patológica. Publicado por Elsevier España, S.L.U. All rights reserved.
MeSH terms
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Adenoma / chemistry
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Adenoma / diagnostic imaging*
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Adenoma / pathology
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Adenoma / surgery
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Adult
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Biomarkers, Tumor / analysis
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Choristoma / diagnostic imaging*
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Choristoma / metabolism
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Choristoma / pathology
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Choristoma / surgery
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Diagnosis, Differential
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Diagnostic Errors
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Empty Sella Syndrome / diagnostic imaging
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Empty Sella Syndrome / etiology*
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Female
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Humans
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Magnetic Resonance Imaging
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Neoplasm Proteins / analysis
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Neuroendocrine Tumors / diagnosis
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Osteolysis / etiology
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Paranasal Sinus Neoplasms / chemistry
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Paranasal Sinus Neoplasms / diagnostic imaging*
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Paranasal Sinus Neoplasms / pathology
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Paranasal Sinus Neoplasms / surgery
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Pituitary Hormones, Anterior / analysis
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Pituitary Neoplasms / chemistry
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Pituitary Neoplasms / diagnostic imaging*
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Pituitary Neoplasms / pathology
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Pituitary Neoplasms / surgery
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Sphenoid Sinus / chemistry
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Sphenoid Sinus / diagnostic imaging*
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Sphenoid Sinus / pathology
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Sphenoid Sinus / surgery
Substances
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Biomarkers, Tumor
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Neoplasm Proteins
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Pituitary Hormones, Anterior