Identification of Distant Metastases From Recurrent Gliosarcoma Using Whole-Body 18F-FDG PET/CT

Clin Nucl Med. 2019 Nov;44(11):923-924. doi: 10.1097/RLU.0000000000002790.

Abstract

A 51-year-old man presented with recurrent gliosarcoma and increasing cough over the last months. On F-FDG PET/CT, solid lung masses with high F-FDG uptake were present. A biopsy taken from a lung lesion indicated distant metastases from gliosarcoma. Gliosarcoma, a rare malignant central nervous system tumor, presents with extracranial metastases in only less than 10%. As highlighted by this case, F-FDG PET/CT can be used for whole-body staging in patients with metastatic brain tumor. Vice versa, highly F-FDG-avid lung lesions in patients with brain tumors should lead to distant metastases as differential diagnosis despite their rare occurrence.

Publication types

  • Case Reports

MeSH terms

  • Fluorodeoxyglucose F18*
  • Gliosarcoma / diagnostic imaging*
  • Gliosarcoma / pathology*
  • Humans
  • Lung Neoplasms / secondary
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Positron Emission Tomography Computed Tomography*
  • Recurrence
  • Whole Body Imaging*

Substances

  • Fluorodeoxyglucose F18