Cutaneous angiomas in POEMS syndrome

J Am Acad Dermatol. 1985 May;12(5 Pt 2):961-4. doi: 10.1016/s0190-9622(85)70123-5.

Abstract

POEMS syndrome is an unusual plasma cell dyscrasia with multisystemic manifestations featuring polyneuropathy, organomegaly, endocrinopathy, M protein and constant skin involvement. We have seen a 58-year-old white man presenting with generalized eruptive angiomas as a rare skin manifestation of this syndrome. We review the literature and discuss the pathogenesis of vascular proliferation in this unusual entity.

Publication types

  • Case Reports

MeSH terms

  • Cardiomegaly / complications*
  • Endocrine System Diseases / complications*
  • Glycoproteins / biosynthesis*
  • Hemangioma / etiology*
  • Hepatomegaly / complications*
  • Humans
  • Kidney Diseases / complications*
  • Male
  • Middle Aged
  • Nervous System Diseases / complications*
  • Paraproteinemias / complications
  • Skin Diseases / complications*
  • Skin Neoplasms / etiology*
  • Syndrome

Substances

  • Glycoproteins
  • protein M (glycoprotein)