A Gut Check Explains Improved Glucose Metabolism after Surgery

Blandine Laferrère; François Pattou

doi:10.1016/j.cmet.2019.10.002

A Gut Check Explains Improved Glucose Metabolism after Surgery

Cell Metab. 2019 Nov 5;30(5):852-854. doi: 10.1016/j.cmet.2019.10.002.

Authors

Blandine Laferrère¹, François Pattou²

Affiliations

¹ New York Obesity Research Center, Division of Endocrinology, Department of Medicine, Columbia University Medical Center, New York, NY, USA. Electronic address: bbl14@columbia.edu.
² Université de Lille, Inserm, CHU Lille, U1190 - European Genomic Institute for Diabetes, 59000 Lille, France.

Abstract

Biliopancreatic diversion (BPD) surgery leads to more frequent diabetes remission than Roux-en-Y gastric bypass (RYGB). In this issue, Harris et al. (2019) compare each surgery after careful matching for percentage weight loss and find the gut as a major site of difference between the effects of the two surgeries.

Publication types

Comment

MeSH terms

Biliopancreatic Diversion*
Gastric Bypass*
Gastrointestinal Microbiome*
Glucose
Humans
Obesity, Morbid / surgery*
Weight Loss

Substances

Glucose

Abstract

Publication types

MeSH terms

Substances

Grants and funding