Malignant Soft-Tissue Sarcomas

Jeremy M Brownstein; Thomas F DeLaney

doi:10.1016/j.hoc.2019.08.022

Malignant Soft-Tissue Sarcomas

Hematol Oncol Clin North Am. 2020 Feb;34(1):161-175. doi: 10.1016/j.hoc.2019.08.022. Epub 2019 Oct 28.

Authors

Jeremy M Brownstein¹, Thomas F DeLaney²

Affiliations

¹ Francis H. Burr Proton Beam Therapy Center, Massachusetts General Hospital, 30 Fruit Street, Boston, MA 02114, USA.
² Department of Radiation Oncology, Francis H. Burr Proton Beam Therapy Center, Massachusetts General Hospital, Harvard Medical School, 30 Fruit Street, Boston, MA 02114, USA. Electronic address: tdelaney@partners.org.

PMID: 31739942
DOI: 10.1016/j.hoc.2019.08.022

Abstract

Soft-tissue sarcomas are cancerous growths of mesenchymal tissues, most commonly arising from fat, muscles, and other connective tissues. Sarcomas are rare, representing only a small fraction of solid malignant tumors. Because of their scarcity and a relative paucity of data, the management of sarcomas can be challenging, especially for those who infrequently encounter these tumors. Herein, the authors review the current literature regarding the diagnosis, workup, and treatment of adult soft-tissue sarcomas.

Keywords: Extremity sarcoma; Radiation therapy; Retroperitoneal sarcoma; Soft-tissue sarcoma.

Publication types

Review

MeSH terms

Adult
Humans
Sarcoma / diagnosis*
Sarcoma / therapy*