Epileptic Spikes in EEG and Migraine Attacks in the Course of Cannabis Withdrawal: A Case Report

Clin EEG Neurosci. 2020 Jan;51(1):45-50. doi: 10.1177/1550059419886704. Epub 2019 Nov 19.

Abstract

In psychiatry, routine EEGs are often abnormal and not very specific, raising questions about the clinical relevance and consequences of potential anomalies. One such question is whether the administration of anticonvulsants would be useful if epileptic discharges are detected in patients without any clinical correlates. With regard to this question, we present a case study in which abnormal EEG patterns were observed in a patient with chronic migraine and cannabis addiction. The patient was a 34-year-old woman with a 14-year history of cannabis abuse who, during withdrawal, showed epileptic spikes, without any corresponding clinical symptoms, and migraine attacks of increasing intensity and frequency. This case study is in line with the new DSM-5 diagnostic tool that for the first time includes the diagnosis of cannabis withdrawal.

Keywords: EEG; cannabis; epileptic spikes; migraine; withdrawal.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticonvulsants / therapeutic use
  • Brain / physiopathology
  • Cannabis / adverse effects*
  • Electroencephalography* / methods
  • Epilepsy / complications*
  • Epilepsy / diagnosis
  • Epilepsy / physiopathology
  • Female
  • Humans
  • Migraine Disorders / complications*
  • Migraine Disorders / diagnosis
  • Migraine Disorders / physiopathology
  • Substance Withdrawal Syndrome*

Substances

  • Anticonvulsants