Drug-induced hypersensitivity syndrome with myocardial involvement treated with tofacitinib

William E Damsky; Matthew D Vesely; Alfred Ian Lee; Jaehyuk Choi; Ana-Claire Meyer; Michael Chen; Tariq Ahmad; Brett King

doi:10.1016/j.jdcr.2019.07.004

Drug-induced hypersensitivity syndrome with myocardial involvement treated with tofacitinib

JAAD Case Rep. 2019 Nov 13;5(12):1018-1026. doi: 10.1016/j.jdcr.2019.07.004. eCollection 2019 Dec.

Authors

William E Damsky¹, Matthew D Vesely¹, Alfred Ian Lee², Jaehyuk Choi³, Ana-Claire Meyer^{4

5}, Michael Chen⁶, Tariq Ahmad⁶, Brett King¹

Affiliations

¹ Department of Dermatology, Yale School of Medicine, New Haven, Connecticut.
² Department of Internal Medicine, Section of Hematology, Yale School of Medicine, New Haven, Connecticut.
³ Department of Dermatology, Northwestern School of Medicine, Chicago, Illinois.
⁴ Department of Neurology, Department of Medicine, Yale School of Medicine, New Haven, Connecticut.
⁵ US Army Medical Research and Material Command.
⁶ Department of Internal Medicine, Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, Connecticut.

No abstract available

Keywords: ANEM, Acute necrotizing eosinophilic myocarditis; CCL, C-C motif chemokine ligand; DIHS; DIHS, drug induced hypersensitivity syndrome; DRESS; IL, interleukin; JAK inhibitor; JAK, Janus kinase; Janus kinase; LVEF, left ventricular ejection fraction; RegiSCAR, Registry of Severe Cutaneous Adverse drug Reactions; STAT, signal transducer and activator of transcription; acute necrotizing eosinophilic myocarditits; drug reaction with eosinophilia and systemic symptoms; drug-induced hypersensitivity syndrome; tofacitinib.

Publication types

Case Reports

Publication types

Grants and funding